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The episode is unique in its storytelling, framed through a therapy session between and his psychiatrist, Dr. Nolan . House recounts a recent case involving an unidentified woman (guest star Sasha Alexander ) who arrived at the Princeton-Plainsboro emergency room with total amnesia and an unexplained illness after collapsing during a run. Key Plot Points

House works to piece together the patient's identity and medical history using physical clues from her running gear and behavioral patterns. Watch www xrysoi se House S06E21 HDTV

Parallel to the case, House deals with significant "baggage" in his personal life. Wilson asks House to move out of their shared condo because Wilson’s ex-wife, Sam , is moving back in. The episode is unique in its storytelling, framed