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The story of the first season of follows the intense professional and personal lives of five surgical interns at the fictional Seattle Grace Hospital. The Core Storyline

: The interns work under the strict supervision of resident Dr. Miranda Bailey (nicknamed "The Nazi") and Chief of Surgery Richard Webber. Key Conflicts :

Cristina begins a relationship with cardiothoracic surgeon Dr. Preston Burke.

(Katherine Heigl): A former model who struggles to be taken seriously.

Throughout the first few months of their program, these doctors face life-or-death medical cases while discovering that neither medicine nor their relationships can be defined in simple black and white. AI responses may include mistakes. Learn more

(Sandra Oh): Highly competitive and ambitious.

: The series begins with Meredith Grey (Ellen Pompeo), the daughter of renowned surgeon Ellis Grey, starting her internship. On her first day, she discovers that her recent one-night stand is actually Dr. Derek Shepherd (Patrick Dempsey), her new attending physician and boss.