Interpretation relies on comparing 24-hour excretion levels against established reference ranges.

Primarily used as a marker for neuroblastoma in children, often analyzed alongside VMA and HVA. Adult Reference Ranges (Approximate): Epinephrine: < 18.3 µg/24h or < 30 µg/24h Norepinephrine: < 84.6 µg/24h or < 60 µg/24h Dopamine: < 459.6 µg/24h or < 600 µg/24h 3. 24-Hour Collection Protocol

This guide outlines the clinical interpretation, collection procedures, and reference standards for urinary catecholamine testing, primarily used to diagnose neuroendocrine tumors.

A typically benign adrenal gland tumor in adults that causes excessive hormone production.

A result three times higher than the upper reference limit strongly indicates a neuroendocrine tumor. Minor increases (less than double) may stem from stress, drugs, or collection errors.

Catecholamines Fractionated by LC-MS/MS, Urine Free - ARUP Lab

Cases of unusually severe or intermittent high blood pressure, especially before age 20.

Rare tumors outside the adrenal glands that secrete similar hormones. 2. Interpretation of Results