The issue features high-production photo spreads, including "naked celebrities" and the world's most prominent adult performers.

Recurring features include "nasty comics" and "gut-busting satire," often targeting political hypocrisy—a hallmark of the magazine since its inception.

True to the brand's long-standing formula, the 2022 Anniversary issue blends high-intensity adult content with the satirical and political commentary that defined Flynt's career.