Download Embolie Pulmonaire Aiguг« - Pdf

: Obstruction causes a ventilation-to-perfusion ( ) mismatch, leading to hypoxemia and respiratory distress. Diagnostic Framework

Acute Pulmonary Embolism (PE) is a critical cardiovascular emergency characterized by the sudden obstruction of a pulmonary artery, typically by a blood clot originating from deep vein thrombosis (DVT) in the lower limbs. As a leading cause of in-hospital mortality, its management requires rapid risk stratification and adherence to standardized clinical guidelines. Pathophysiology and Etiology

: Once a clot lodges in the pulmonary vascular bed, it increases pulmonary vascular resistance, which can lead to acute right ventricular (RV) failure and hemodynamic collapse. Download Embolie pulmonaire aiguГ« pdf

: Roughly 70% to 80% of emboli arise from proximal deep veins in the legs or pelvis.

Treatment strategies are dictated by the patient's hemodynamic stability and risk category. Pathophysiology and Etiology : Once a clot lodges

: For high-risk (hemodynamically unstable) patients, systemic thrombolysis (e.g., Alteplase) is recommended to rapidly dissolve the clot.

: D-dimer testing is highly sensitive for ruling out PE in low-to-intermediate risk patients. Cardiac biomarkers like Troponin and BNP help assess myocardial injury and RV strain. : For high-risk (hemodynamically unstable) patients

: When thrombolysis is contraindicated or fails, options include catheter-directed thrombectomy or surgical embolectomy. Prognosis and Follow-Up