Bmp4 -

: It primarily signals through two routes:

Beyond development, BMP4 is a major player in adult metabolism and disease. : It primarily signals through two routes: Beyond

: Binding to Type I (ALK3/ALK6) and Type II (BMPR2) receptors triggers the phosphorylation of R-Smads (Smad1/5/8) , which complex with Smad4 and move into the nucleus to regulate gene expression. : It primarily signals through two routes: Beyond